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Yusuf Hamied Department of Chemistry

 

Recent Publications from the Synthesis Research Interest Group

Supramolecular assembly properties of a mixed-sequence recognition-encoded melamine oligomer
M Dhiman, JT Smith, CA Hunter
– Organic & biomolecular chemistry
(2025)
(DOI: 10.1039/d5ob00769k)
Detecting alpha-synuclein aggregates with small molecules on single-molecule array
JYL Lam, TS Chisholm, H Almahli, EA English, Z Xia, Y Wu, MR Cheetham, CA Hunter, D Klenerman
– Chemical science
(2025)
(DOI: 10.1039/d4sc07649d)
Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
– Angewandte Chemie
(2025)
e202507532
(DOI: 10.1002/ange.202507532)
Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
– Angewandte Chemie International Edition
(2025)
e202507532
(DOI: 10.1002/anie.202507532)
Prediction of Solution Phase Association Constants by Mapping Contact Points in Intermolecular Complexes
KJ Zator, CA Hunter
– Physical Chemistry Chemical Physics
(2025)
27,
11343
(DOI: 10.1039/d5cp00398a)
Machine Learning-Driven Optimization of Continuous-Flow Photoredox Amine Synthesis
P Jorayev, S Soritz, S Sung, MI Jeraal, D Russo, A Barthelme, FC Toussaint, MJ Gaunt, AA Lapkin
– Organic Process Research & Development
(2025)
29,
1411
(DOI: 10.1021/acs.oprd.4c00533)
One-carbon homologation of alkenes
MC Grocott, MJ Gaunt
– Nature
(2025)
643,
130
(DOI: 10.1038/s41586-025-09159-9)
Template-Directed Synthesis of Recognition-Encoded Melamine Oligomers using a Base-Filling Strategy.
JT Smith, J Baixeras Buye, B Iddon, DO Soloviev, CA Hunter
– Journal of the American Chemical Society
(2025)
147,
18284
(DOI: 10.1021/jacs.5c05681)
Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
– Angewandte Chemie (International ed. in English)
(2025)
64,
e202507532
(DOI: 10.1002/anie.202507532)
A Platform for SpyCatcher Conjugation to Native Antibodies
S Krajcovicova, T Wharton, CL Driscoll, TA King, MR Howarth, DR Spring
– Chemical Science
(2025)
16,
10602
(DOI: 10.1039/d5sc02286j)
Ligands for Protein Fibrils of Amyloid-β, α-Synuclein, and Tau
TS Chisholm, CA Hunter
– Chemical Reviews
(2025)
125,
5282
(DOI: 10.1021/acs.chemrev.4c00838)
Solvation energies from atomic surface site interaction points
E Gross, MD Driver, A Saif, ON Evans, CA Hunter
– Physical Chemistry Chemical Physics
(2025)
27,
8844
(DOI: 10.1039/d5cp00635j)
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, EJ Fisher, M Zacharopoulou, F Ferrer, D Barford, D Spring, C Lindon, C Phillips, LS Itzhaki
(2025)
(DOI: 10.7554/elife.104238.2)
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, EJ Fisher, M Zacharopoulou, F Ferrer, D Barford, D Spring, C Lindon, C Phillips, LS Itzhaki
(2025)
(DOI: 10.7554/elife.104238)
The supramolecular chemistry of monodisperse 1,3,5-triazine oligomers.
L Escobar, CA Hunter
– Org Biomol Chem
(2025)
23,
3520
(DOI: 10.1039/d5ob00321k)
Quantification of the effects of n-π* interactions on the H-bonding properties of amide groups
FE Hanna, AD Bond, CA Hunter
– Chemical Science
(2025)
16,
7894
(DOI: 10.1039/d4sc08331h)
Relationship between interaction geometry and cooperativity measured in H-bonded networks of hydroxyl groups
L Trevisan, AD Bond, CA Hunter
– Chemical Science
(2025)
16,
7418
(DOI: 10.1039/d5sc00784d)
Methods for the Generation of Single‐Payload Antibody‐Drug Conjugates
T Wharton, DR Spring
– Chemmedchem
(2025)
20,
e202500132
(DOI: 10.1002/cmdc.202500132)
Straightforward, Scalable, Solution-Phase Synthesis of Peptide Bonds in Flow.
ZE Wilson, E Lopez, NJ Flodén, C Watkins, G Bianchini, SV Ley
– Journal of Flow Chemistry
(2025)
15,
67
(DOI: 10.1007/s41981-025-00347-2)
Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity
M Wang, P Medarametla, T Kronenberger, T Deingruber, P Brear, W Figueroa, P-M Ho, T Krueger, JC Pearce, A Poso, JG Wakefield, DR Spring, M Welch
– Nature Communications
(2025)
16,
2334
(DOI: 10.1038/s41467-025-57532-z)

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